Prebiotic Study

We are looking for volunteers to enroll a clinical research study that will evaluate a natural health product, XOS95™.

XOS95™ is a xylooligosaccharide which is extracted from sugar cane. Xylooligosaccharides are polymers of the sugar xylose. A polymer is a large molecule that is composed of several repeating subunits.

This is a randomized and double-blind study. Double-blind refers to that you nor the staff at Nutrasource will know which study group you have been placed in. However, for your safety, a staff member not involved at Nutrasource is fully aware what group you are and the information can be made available if there any health concerns because of the study.

The purpose of this study is to see if XOS95™ changes the number and type of bacteria that are naturally occurring in your intestines. Also, we are looking to see if XOS95™ reduces other markers of general health including weight, blood sugar and cholesterol.

This study has a total of four clinic visits which will take approximately 30 minutes to 4 hours.

  • Visit 1 (Screening visit): Approx. 60-90 minutes.
  • Visit 2: Approx. 4-5 hours.
  • Visit 3: Approx. 30 to 60 minutes.
  • Visit 4: Approx. 4-5 hours.

Oral Glucose Tolerance Test

  • At visits 2 and 4, you will be given a sweet drink that contains 75g of glucose (sugar) and blood will drawn over the next 4 hours. This test will measure your blood sugar response and insulin response. The amount of blood drawn at one of these visits is roughly 3 tablespoons.

If you choose to, and are eligible to participate, you will be in the study for approximately 12 weeks. You will be asked to come to the clinic fasting (nothing to eat or drink except water) for at least 12 hours for all four visits. You will also be asked to provide 4 blood samples and 3 fecal(stool) samples. You will be asked to record the foods you eat three days prior to the first stool collection and eat these same foods three days prior to each stool collection. This helps to minimize any effects that food have on bacteria present in the stool sample.

If you are eligible to participate in the study and complete the study, you will be reimbursed a total of $400.00 for your time and travel to the clinic.

Find out if you are eligible for this study by completing the screening survey.



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